John Constantine, a cynical occult detective with the ability to see angels and demons, is doomed to eternal damnation for a past suicide attempt.
To earn redemption, he exorcises demons back to Hell. Police detective Angela Dodson seeks his help when her twin sister Isabel, who shared psychic abilities, mysteriously dies by suicide. Together, they uncover a plot by the arch-demon Mammon and the rogue angel Gabriel to bring Hell to Earth using the Spear of Destiny. In a final confrontation, Constantine sacrifices himself to trick Lucifer into stopping Mammon and Gabriel. Lucifer heals Constantine’s cancer as a “reward,” but Constantine secures a chance at redemption. The film ends with Constantine continuing his fight against dark forces, embracing his role with renewed purpose.